So I've been piecing together my first proper off-grid setup for a converted Sprinter and I've gone back and forth on this more times than I care to admit. Ended up going 24V after a lot of head-scratching — running a 200Ah lithium bank (two 100Ah 24V cells in parallel), a Victron MultiPlus-II 24/3000 and about 600W of solar through an MPPT 100/30. Wiring is noticeably neater at 24V with thinner cable runs, which matters in a van build where every millimetre counts.
The bit that really threw me early on was the 12V appliance problem. Most of the "van life" gear — compressor fridges, diesel heaters, USB hubs — assumes 12V. I'm running a Fog City 12V compressor fridge and had to stick a Victron Orion-Tr 24/12-18A DC-DC converter in the mix, which works perfectly but adds cost and complexity I hadn't budgeted for initially. Anyone else hit that same wall?
Also curious whether people running smaller setups — say under 400W solar and a modest 100Ah bank — would bother with 24V at all, or whether 12V is just the sensible default at that scale. I've seen arguments both ways and I'm not sure the efficiency gains at lower current really justify the awkwardness until you're pulling serious wattage.