Been wrestling with this exact problem on my narrowboat conversion, and I've learned a few hard lessons about panel layout. The temptation is to cram everything into one central hub, but honestly, that's a recipe for chaos when you're troubleshooting at midnight in the middle of nowhere.
What's worked for me is splitting things logically: main breakers and battery isolators front and centre, then grouping circuits by function. Solar gear on one side, domestic loads on the other. Sounds daft, but when your water heater trips and you're bleary-eyed, you want to know exactly where to look.
The physical arrangement matters too. I mounted my Victron breaker panel vertically at eye level rather than tucking it away—saves hours of faffing about with a torch. Left plenty of space behind it for cable management; snug wiring leads to overheating and fried components. Use proper marine-grade labelling (not the printer ones that peel off after three months).
Cable sizing's crucial. Most people undersizing the main feeds between battery and panel, which causes voltage drop across the whole system. It's tempting to save a tenner on cable, but it costs you in efficiency and heat generation.
Curious what others have done—particularly those with split systems across a campervan. Are you keeping everything centralized or spreading distribution boxes around? And have you found any breaker brands that don't feel like they'll fail in a year? Been eyeing up some proper industrial-grade switches but they're pricey.